查看“磁共振小组/磁共振兼容/RF-induced heating in tissue near bilateral DBS implants during MRI at 1.5 T and 3T: The role of surgical lead management”的源代码

{{文章推荐|Reason=研究了真实导线植入路径对射频热的影响|Journal=NeuroImage|PubYear=2019|DOI=10.1016/j.neuroimage.2018.09.034|Category_=研究性工作|Domain=磁共振兼容|RecomBy=桑宛萱|RecomGrp=磁共振小组|ReviewBy=姜老师|Abstract=Access to MRI is limited for patients with deep brain stimulation (DBS) implants due to safety hazards, including radiofrequency (RF) heating of tissue surrounding the leads. Computational models provide an exquisite tool to explore the multi-variate problem of RF heating and help better understand the interaction of electromagnetic ﬁelds and biological tissues. This paper presents a computational approach to assess RF-induced heating, in terms of speciﬁc absorption rate (SAR) in the tissue, around the tip of bilateral DBS leads during MRI at 64MHz/1.5 T and 127 MHz/3T. Patient-speciﬁc realistic lead models were constructed from post-operative CT images of nine patients operated for sub-thalamic nucleus DBS. Finite element method was applied to calculate the SAR at the tip of left and right DBS contact electrodes. Both transmit head coils and transmit body coils were analyzed. We found a substantial difference between the SAR and temperature rise at the tip of right and left DBS leads, with the lead contralateral to the implanted pulse generator (IPG) exhibiting up to 7 times higher SAR in simulations, and up to 10 times higher temperature rise during measurements. The orientation of incident electric ﬁeld with respect to lead trajectories was explored and a metric to predict local SAR ampliﬁcation was introduced. Modiﬁcation of the lead trajectory was shown to substantially reduce the heating in phantom experiments using both conductive wires and commercially available DBS leads. Finally, the surgical feasibility of implementing the modiﬁed trajectories was demonstrated in a patient operated for bilateral DBS.|DetaialsDM=射频热电磁计算|Citation_=110}}