Electrical stimulation of excitable tissue: design of efficacious and safe protocols
推荐理由
综述了刺激可兴奋组织的原理,以及刺激过程中对组织和电极的损伤机制。
文章简介 | |
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期刊 | Journal of Neuroscience Methods |
发表年份 | 2005 |
DOI | 10.1016/j.jneumeth.2004.10.020 |
类型 | 研究性工作 |
领域 | 神经电刺激 |
引用量 | 2360 |
推荐信息 | |
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推荐人 | 顾忆元 |
审核 | 姜老师 |
推荐小组 | 磁共振小组 |
摘要
The physical basis for electrical stimulation of excitable tissue, as used by electrophysiological researchers and clinicians in functional electrical stimulation, is presented with emphasis on the fundamental mechanisms of charge injection at the electrode/tissue interface. Faradaic and non-Faradaic charge transfer mechanisms are presented and contrasted. An electrical model of the electrode/tissue interface is given. The physical basis for the origin of electrode potentials is given. Various methods of controlling charge delivery during pulsing are presented. Electrochemical reversibility is discussed. Commonly used electrode materials and stimulation protocols are reviewed in terms of stimulation efficacy and safety. Principles of stimulation of excitable tissue are reviewed with emphasis on efficacy and safety. Mechanisms of damage to tissue and the electrode are reviewed.
细分领域
< | 刺激波形和组织安全